Micro-RNAs (miRNAs) control gene expression at the post-transcriptional level and are widely involved in carcinogenesis, playing a role as both oncogenes and tumor suppressors.MiRNAs act as potent therapeutic weapon in cancer, but their potential therapeutic use is limited by the off-target effect due to their nonspecific distribution in Multi-Tool
It is well known that a specific set of genetic and non-genetic risk factors contributes to the onset of Alzheimer disease (AD).Non-genetic risk factors include diabetes, hypertension in mid-life, and probably dyslipidemia in mid-life.This review focuses on the vascular and metabolic components of non-genetic risk factors.The mechanisms whereby non
The notions of a collaborative virtual power plant ecosystem (CVPP-E) and a cognitive household digital twin (CHDT) have been proposed as contributions to the efficient organization and management of households within renewable energy communities (RECs).CHDTs can be modeled as software agents that are designed to possess some cognitive capabilities
ABSTRACT The global spread of Plasmodium falciparum chloroquine resistance transporter (PfCRT) variant haplotypes earlier caused the widespread loss of chloroquine (CQ) efficacy.In Asia, novel PfCRT mutations that emerged on the Dd2 allelic background have recently been implicated in high-level resistance to piperaquine, and N326S and I356T have be
Microplastic contamination, like other global change factors, can induce effects on ecosystem functions and processes, affecting various soil biophysical properties.However, effects of such contaminants on nutrient cycles in agroecosystems are still poorly understood.We here performed two pot experiments to investigate the effect of polyester micro